Molecular mechanisms of T cell receptor dysfunction induced by human immunodeficiency virus type 1 envelope protein

Acquired Immunodeficiency Syndrome (AIDS) is characterized by severe immunodeficiency and lymphopenia, with dramatic loss of CD4+ T cells. Yet prior to the destruction of this population, CD4+ T cells isolated from asymptomatic Human Immunodeficiency Virus-type 1 (HIV-1) seropositive individuals exh...

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Bibliographic Details
Main Author: Maitland, Anne Lydia
Corporate Author: University of Pennsylvania
Other Authors: Gaulton, Glen N. (advisor)
Format: Thesis Book
Language:English
Subjects:

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