A structural and biochemical analysis of the interaction between the mammalian formin FMNL3 and actin /

" The mammalian formin, FMNL3, plays a critical role in altering cell morphology through direct rearrangement of the actin cytoskeleton. The formin homology 2 (FH2) domain of FMNL3 slows actin filament nucleation and elongation by regulating actin subunit addition at the barbed end of the filam...

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Bibliographic Details
Main Author: Thompson, Morgan E
Corporate Author: Dartmouth Medical School Department of Biochemistry
Format: Thesis Book
Language:English
Published: 2012

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Dartmouth College

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Call Number: Ph.D. 2012