Nitric Oxide and the Cell : Proliferation, Differentiation, and Death /

Nitric oxide has proven to be a molecule with wide biological significance. It is involved in myriad actions which range from physiology to pathophysiology. One of the fundamental questions in relation to its biological relevance concerns the paradoxical nature of some of its actions. For example, t...

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Bibliographic Details
Other Authors: Bagetta, G, Higgs, E. A, Moncada, S, Nisticò, G
Format: Book
Language:English
Published: Princeton, NJ : Princeton University Press, [2017]
Series:Princeton legacy library
Subjects:
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245 0 0 |a Nitric Oxide and the Cell :  |b Proliferation, Differentiation, and Death /  |c E. A. Higgs, G. Bagetta, S. Moncada, G. Nisticò 
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505 0 0 |t Frontmatter --  |t Contents --  |t Preface --  |t Contributors --  |t Abbreviations --  |t 1. Nitric oxide, mitochondria and cytotoxicity --  |t 2. Nitric oxide and its congeners in mitochondria: implications for apoptosis --  |t 3. Interactions between nitric oxide and cytochrome-c oxidase in turnover --  |t 4. Nitric oxide interactions with mitochondria and oxygen metabolism --  |t 5. Resistance factors for nitrosative and oxidative stress --  |t 6. S-Nitrosylation of thiol groups in haemoglobins from various species --  |t 7. Differential inhibitory action of nitric oxide and peroxynitrite on the R2 subunit of ribonucleotide reductase --  |t 8. Hydroxyguanidines as modifiers of cell proliferation and death: a possible role for nitric oxide --  |t 9. Control of cell growth by nitric oxide: the role of cGMP-dependent and -independent events occurring at various steps of growth factor-activated signalling processes --  |t 10. Nitric oxide controls cell proliferation during Drosophila development --  |t 11. Cytoprotective actions of nitric oxide in hepatic inflammation --  |t 12. Activation of nuclear factor-κB and activator protein- I, and steady-state level of mRNA encoding tumour necrosis factor-α and inducible nitric oxide synthase in rat liver during different types of cell proliferation --  |t 13. The mechanism of nitric oxide-induced apoptosis in the pancreatic β-cell may involve cGMP and protein kinase G --  |t 14. Normal and pathological expression of nitric oxide synthase in the central nervous system --  |t 15. The role of astroglial cell-derived nitric oxide and prostanoids in death and repair mechanisms in the brain --  |t 16. Role of nitric oxide and nerve growth factor in the mechanisms of neurotoxicity induced by the HIV-1 coat protein gp l 20 in rat --  |t 17. Mechanisms of neurotoxicity induced by the HIV-1 coat protein, gp l 20, in human neuroblastoma cells in culture --  |t 18. Nitric oxide mediates differentiation and survival of neuronal cells --  |t 19. Neuromodulatory and neuroprotective actions of nitric oxide in the striatum --  |t 20. Microdialysis study in vivo of the nitric oxide/cGMP pathway in the hippocampus and cerebellum of adult and aged rats --  |t 21. Mechanisms of neuronal apoptosis elicited by glutamate or nitric oxide donors --  |t 22. Evidence that nitric oxide induces apoptotic cell death in the lateral geniculate nucleus of dark-reared rabbits --  |t 23. Nitric oxide and prostaglandins in inflammation --  |t 24. A further insight into the mechanism of lipoxygenase inhibition by nitric oxide --  |t 25. The role of nitric oxide in T-cell functions --  |t 26. CD95-induced calcium release and apoptosis are regulated by nitric oxide via a cGMP dependent pathway in human γδ T-lymphocytes --  |t 27. Nitric oxide-initiated apoptotic cell death: activating and antagonistic signalling components --  |t 28. Nitric oxide-induced apoptosis of RAW264.7 peritoneal macrophages: relationship between apoptosis and integrin expression profiles --  |t 29. Nitric oxide, p53 and cancer --  |t 30. The role of nitric oxide in Bacillus Calmette-Guérin-mediated anti-tumour effects in human bladder cancer --  |t 31. Nitric oxide priming inhibits nitric oxide-mediated apoptosis --  |t Subject Index 
520 |a Nitric oxide has proven to be a molecule with wide biological significance. It is involved in myriad actions which range from physiology to pathophysiology. One of the fundamental questions in relation to its biological relevance concerns the paradoxical nature of some of its actions. For example, there is a whole range of effects related to cytoprotection, cell proliferation, differentiation, and cell death. The way in which nitric oxide becomes involved in pathophysiology is slowly being elucidated. This volume contains a summary of the discussions that took place at the Second International Paraelios Symposium on Nitric Oxide research, and will make a significant contribution to this very exciting subject.Originally published in 1998.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905 
538 |a Mode of access: Internet via World Wide Web 
546 |a In English 
588 0 |a Description based on online resource; title from PDF title page (publisher's Web site, viewed 13. Sep 2017) 
596 |a 22 
650 0 |a Cell differentiation  |x Molecular aspects  |v Congresses 
650 0 |a Cell proliferation  |x Molecular aspects  |v Congresses 
650 0 |a Nitric oxide  |x Pathophysiology  |v Congresses 
650 0 |a Nitric oxide  |x Physiological effect  |v Congresses 
700 1 |a Bagetta, G  |? UNAUTHORIZED 
700 1 |a Higgs, E. A  |? UNAUTHORIZED 
700 1 |a Moncada, S  |? UNAUTHORIZED 
700 1 |a Nisticò, G  |? UNAUTHORIZED 
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