Acromegaly : a Century of Scientific and Clinical Progress /

The manuscripts in this volume were contributed by the speakers invited to the Acromegaly Centennial Symposium held in San Francisco, California in July 1986. The meeting was organized to commemorate the description of acromegaly by the French physician Pierre Marie, in 1886. The members of the Scie...

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Bibliographic Details
Main Author: Robbins, Richard J
Other Authors: Melmed, Shlomo
Format: Book
Language:English
Published: Boston, MA : Springer US, 1987
Subjects:
Table of Contents:
  • The Life of Doctor Pierre Marie: A Great Granddaughter-s View
  • I. Molecular Biology and Physiology of GH Action
  • 1. Etiology of Acromegaly from the Neuroendocrine Point of View: A Historical Perspective
  • 2. Human Growth Hormone Gene Regulation in Somatotroph Cell Cultures
  • 3. Detection of the Multiple Forms of Human Growth Hormone
  • 4. Molecular Heterogeneity of Circulating Growth Hormone in Acromegaly
  • 5. Somatomedin Gene Expression
  • 6. Somatomedin Action and Tissue Growth Factor Receptors
  • 7. The Mechanism of the Growth-Promoting Action of Growth Hormone
  • II. Regulation of Growth Hormone Secretion
  • 8. Somatostatin and the Syndrome of Acromegaly
  • 9. Growth Hormone Secretion in Acromegaly
  • 10. Actions of GRF in Man
  • 11. GRF Secretion in Man
  • 12. Ectopic GRH Syndromes
  • III. Diagnosis of Acromegaly
  • 13. Clinical Developments Over the Past 100 Years of Acromegaly
  • 14. Gonadal Steroid Modulation of Growth Hormone Secretory Patterns in the Rat
  • 15. Pathogenesis of Acromegaly
  • 16. Pathology of Acromegaly
  • 17. Associated Hypersecretion of Anterior Pituitary Hormones Other Than Growth Hormone in Acromegaly
  • 18. Effect of Growth Hormone on Carbohydrate and Lipid Metabolism: An Overview
  • 19. The Diagnosis of Acromegaly
  • IV. Treatments for Acromegaly
  • 20. Conventional Supervoltage Radiation in the Treatment of Acromegaly
  • 21. Long-Term Effects of Proton Beam Therapy for Acromegaly
  • 22. Results of Transsphenoidal Resection of Growth Hormone-Secreting Pituitary Adenomas
  • 23. Long-Term Results of Transsphenoidal Surgery for the Management of Acromegaly
  • 24. The Use of Somatostatin Analogs in the Treatment of Acromegaly
  • 25. The Use of Dopamine Agonists in the Management of Acromegaly
  • 26. Decision Analysis of Treatment Options in Acromegaly
  • Author Index