Health risks from exposure to low levels of ionizing radiation : BEIR VII Phase 2 /
| Corporate Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Washington, D.C. :
National Academies Press,
[2006], ©2006
Washington, D.C. : c2006 Washington, D.C. : ©2006 Washington, D.C. : [2006] |
| Series: | BEIR (Series) ;
7, phase 2 |
| Subjects: |
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| 245 | 0 | 0 | |a Health risks from exposure to low levels of ionizing radiation : BEIR VII Phase 2 / |c Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation, Board on Radiation Effects Research, Division on Earth and Life Studies, National Research Council of the National Academies |
| 260 | |a Washington, D.C. : |b National Academies Press, |c [2006], ©2006 | ||
| 260 | |a Washington, D.C. : |b National Academies Press, |c c2006 | ||
| 260 | |a Washington, D.C. : |b National Academies Press, |c ©2006 | ||
| 264 | 1 | |a Washington, D.C. : |b National Academies Press, |c [2006] | |
| 264 | 4 | |c ©2006 | |
| 300 | |a xvi, 406 p. : |b ill. ; |c 28 cm | ||
| 300 | |a xvi, 406 pages : |b illustrations ; |c 28 cm | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a unmediated |b n |2 rdamedia | ||
| 338 | |a volume |b nc |2 rdacarrier | ||
| 490 | 1 | |a BEIR ; |v 7, phase 2 | |
| 500 | |a This is the seventh in a series of reports from the National Research Council prepared to advise the U.S. government on the relationship between exposure to ionizing radiation and human health | ||
| 504 | |a Includes bibliographical references (p. 337-372) and index | ||
| 504 | |a Includes bibliographical references (pages 337-372) and index | ||
| 505 | 0 | |a Background Infomration -- Molecular and Cellullar Response to Ionizing Radiation -- Radiation-Induced Cancer: Mechanisms, Quantitative Experimental Studies, and the Role of Genetic Factors -- Heritable Genetic Effects of Radiation in Human Populations -- Background for Epidemiologic Methods -- A-Bomb Survivor Studies -- Medical Radiation Studies -- Occupational Radiation Studies -- Environmental Radiation Studies -- Inegration of Biology and Epidemiology -- Risk Assessment, Models, and Methods -- Estimating Cancer Risk -- Summary and Research Needs | |
| 505 | 0 | |a Background Information -- Molecular and Cellullar Response to Ionizing Radiation -- Radiation-Induced Cancer: Mechanisms, Quantitative Experimental Studies, and the Role of Genetic Factors -- Heritable Genetic Effects of Radiation in Human Populations -- Background for Epidemiologic Methods -- A-Bomb Survivor Studies -- Medical Radiation Studies -- Occupational Radiation Studies -- Environmental Radiation Studies -- Inegration of Biology and Epidemiology -- Risk Assessment, Models, and Methods -- Estimating Cancer Risk -- Summary and Research Needs | |
| 505 | 0 | 0 | |t How Ionizing Radiation Was Discovered -- |t How Ionizing Radiation Is Detected -- |t Units Used to Describe Radiation Dose -- |t What Is Meant by Low Doses of Ionizing Radiation -- |t Exposure from Natural Background Radiation -- |t Contribution of Man-Made Radiation to Public Exposure -- |t Scenarios Illustrating How People Might Be Exposed to Ionizing Radiation above Background Levels -- |t Evidence for Adverse Health Effects Such as Cancer and Hereditary Disease -- |t The BEIR VII Risk Models -- |t Research Reviewed by the Committee -- |t Evidence from Biology -- |t Estimation of Heritable Genetic Effects of Radiation in Human Populations -- |t Evidence from Epidemiology -- |t Integration of Biology and Epidemiology -- |t Estimating Cancer Risks -- |t Recommended Research Needs -- |g 1 |t Background Information -- |t Physical Aspects of Radiation -- |t Chemical Aspects of Radiation -- |t Molecular Mechanisms of DNA Repair -- |g Annex 1A. |t Ionizing Radiation and Oxidative Damage-A Viewpoint from Saccharomyces cerevisiae -- |g 2. |t Molecular and Cellular Responses to Ionizing Radiation -- |t General Aspects of Dose-Response Relationships -- |t Induction of Chromosome Aberrations -- |t Induction of Gene Mutations in Somatic Cells -- |t Radiation-Induced Genomic Instability -- |t Cell Cycle Effects -- |t Adaptive Response -- |t Bystander Effects -- |t Hyper-Radiation Sensitivity at Low Doses -- |t Observed Dose-Response Relationships at Low Doses -- |g 3. |t Radiation-Induced Cancer: Mechanisms, Quantitative Experimental Studies, and the Role of Genetic Factors -- |t Mechanisms of Tumorigenesis -- |t Radiation-Induced Genomic Instability in Radiation Tumorigenesis -- |t Quantitative Studies in Experimental Tumorigenesis -- |t Genetic Susceptibility to Radiation-Induced Cancer -- |g 4. |t Heritable Genetic Effects of Radiation in Human Populations -- |t Introduction and Brief History -- |t General Framework -- |t Genetic Diseases -- |t Risk Estimation Methods -- |t Recent Advances with Respect to the Three Quantities Used with the DD Method of Risk Estimation -- |t The Doubling Dose Estimate -- |t Mutation Component of Genetic Diseases -- |t MC Estimation for Chronic Multifactorial Disease -- |t Other Potentially Relevant Data -- |t Risk Estimation -- |g Annex 4A. |t Models of Inheritance of Multifactorial Diseases in the Population -- |g Annex 4B. |t The Doubling Dose -- |g Annex 4C. |t Assumptions and Specifications of the Finite-Locus Threshold Model -- |g Annex 4D. |t Differences Between Spontaneous Disease-Causing Mutations in Humans and Radiation-Induced Mutations in Experimental Systems -- |g Annex 4E. |t Criteria Used to Assign Human Genes to One of Three Groups from the Standpoint of the Recoverability of Induced Mutations in Live Births -- |g Annex 4F. |t Radiation Studies with Expanded Simple Tandem Repeat Loci in the Mouse and Minisatellite Loci in Human Germ Cells -- |g Annex 4G. |t Doubling Doses Estimated from Genetic Data of Children of A-Bomb Survivors -- |g 5. |t Background for Epidemiologic Methods -- |t Collection of Epidemiologic Data -- |t Analysis of Epidemiologic Data -- |t Interpretation of Epidemiologic Data -- |g 6. |t Atomic Bomb Survivor Studies -- |t Description of the Cohort -- |t Statistical Methods -- |t All Solid Cancers -- |t Site-Specific Cancers -- |t Cancers Resulting from Exposure In Utero -- |t Benign Neoplasms -- |t Nonneoplastic Disease -- |t Life Shortening -- |g 7. |t Medical Radiation Studies -- |t Medical Uses of Radiation -- |t Evaluation of Risk for Specific Cancer Sites -- |g 8. |t Occupational Radiation Studies -- |t Nuclear Industry Workers -- |t Workers from the Mayak Facility -- |t Chernobyl Cleanup Workers -- |t Airline and Aerospace Employees -- |t Medical and Dental Occupational Exposures -- |g 9. |t Environmental Radiation Studies -- |t Populations Living Around Nuclear Facilities -- |t Populations Exposed from Atmospheric Testing, Fallout, or Other Environmental Release of Radiation -- |t Populations Exposed from the Chernobyl Accident -- |t Populations Exposed from Natural Background -- |t Children of Adults Exposed to Radiation -- |t Exposure to Radioactive Iodine 131 -- |g 10. |t Integration of Biology and Epidemiology -- |t DNA Damage Response and Cancer Risk -- |t Projection of Risks Over Time -- |t The Transport of Cancer Risk Between Different Populations -- |t Form of the Dose-Response for Radiation Tumorigenesis -- |t Dose and Dose-Rate Effects on Tumor Induction -- |t Other Forms of Cellular and Animal Response to Radiation -- |t Genetic Susceptibility to Cancer -- |t Heritable Effects of Radiation -- |g Annex 10A. |t Application of the Moolgavkar and Knudson Two-Stage Clonal Expansion Model to the Transport of Radiation Cancer Risk -- |g Annex 10B. |t Evidence for the Connection Between Dose Effects and Dose-Rate Effects in Animal Experiments -- |g 11. |t Risk Assessment Models and Methods -- |t Risk Assessment Methodology -- |t Risk Models -- |t Variables That Modify the Dose-Response Relationship -- |g 12. |t Estimating Cancer Risk -- |t Data Evaluated for BEIR VII Models -- |t Measures of Risk and Choice of Cancer End Points -- |t The BEIR VII Committee's Preferred Models -- |t Use of the Committee's Preferred Models to Estimate Risks for the U.S. Population -- |t Quantitative Evaluation of Uncertainty in Lifetime Risks -- |t Results of Risk Calculations -- |t Uncertainties in Lifetime Risk Estimates -- |t Coherence of Models with Other Studies -- |g Annex 12A. |t Previous Models for Estimating Cancer Risks from Exposure to Low Levels of Low-LET Ionizing Radiation -- |g Annex 12B. |t Committee Analyses of Data on the LSS Cohort to Develop BEIR VII Models for Estimating Cancer Risks -- |g Annex 12C. |t Details of LAR Uncertainty Analysis -- |g Annex 12D. |t Additional Examples of Lifetime Risk Estimates Based on BEIR VII Preferred Models -- |g 13. |t Summary and Research Needs -- |t Evidence from Biology -- |t Genetic Effects of Radiation on Human Populations -- |t Epidemiologic Studies of Populations Exposed to Ionizing Radiation -- |t Integration of Biology and Epidemiology -- |t Models for Estimating the Lifetime Risk of Cancer -- |g A. |t Basic Biological and Genetic Concepts -- |g B. |t Commentary on "Radiation From Medical Procedures in the Pathogenesis of Cancer and Ischemic Heart Disease: Dose-Response Studies with Physicians Per 100,000 Population" -- |g C. |t Issues Raised by the Institute for Energy and Environment Research (IEER) -- |g D. |t Hormesis -- |g E. |t Fifteen-Country Workers Study. |
| 505 | 0 | 0 | |t How Ionizing Radiation Was Discovered -- |t How Ionizing Radiation Is Detected -- |t Units Used to Describe Radiation Dose -- |t What Is Meant by Low Doses of Ionizing Radiation -- |t Exposure from Natural Background Radiation -- |t Contribution of Man-Made Radiation to Public Exposure -- |t Scenarios Illustrating How People Might Be Exposed to Ionizing Radiation above Background Levels -- |t Evidence for Adverse Health Effects Such as Cancer and Hereditary Disease -- |t The BEIR VII Risk Models -- |t Research Reviewed by the Committee -- |t Evidence from Biology -- |t Estimation of Heritable Genetic Effects of Radiation in Human Populations -- |t Evidence from Epidemiology -- |t Integration of Biology and Epidemiology -- |t Estimating Cancer Risks -- |t Recommended Research Needs -- |g 1 |t Background Information -- |t Physical Aspects of Radiation -- |t Chemical Aspects of Radiation -- |t Molecular Mechanisms of DNA Repair -- |g Annex 1A. |t Ionizing Radiation and Oxidative Damage-A Viewpoint from Saccharomyces cerevisiae -- |g 2. |t Molecular and Cellular Responses to Ionizing Radiation -- |t General Aspects of Dose-Response Relationships -- |t Induction of Chromosome Aberrations -- |t Induction of Gene Mutations in Somatic Cells -- |t Radiation-Induced Genomic Instability -- |t Cell Cycle Effects -- |t Adaptive Response -- |t Bystander Effects -- |t Hyper-Radiation Sensitivity at Low Doses -- |t Observed Dose-Response Relationships at Low Doses -- |g 3. |t Radiation-Induced Cancer: Mechanisms, Quantitative Experimental Studies, and the Role of Genetic Factors -- |t Mechanisms of Tumorigenesis -- |t Radiation-Induced Genomic Instability in Radiation Tumorigenesis -- |t Quantitative Studies in Experimental Tumorigenesis -- |t Genetic Susceptibility to Radiation-Induced Cancer -- |g 4. |t Heritable Genetic Effects of Radiation in Human Populations -- |t Introduction and Brief History -- |t General Framework -- |t Genetic Diseases -- |t Risk Estimation Methods -- |
| 505 | 0 | 0 | |t How Ionizing Radiation Was Discovered |g 1 -- |t How Ionizing Radiation Is Detected |g 2 -- |t Units Used to Describe Radiation Dose |g 2 -- |t What Is Meant by Low Doses of Ionizing Radiation |g 2 -- |t Exposure from Natural Background Radiation |g 3 -- |t Contribution of Man-Made Radiation to Public Exposure |g 3 -- |t Scenarios Illustrating How People Might Be Exposed to Ionizing Radiation above Background Levels |g 4 -- |t Evidence for Adverse Health Effects Such as Cancer and Hereditary Disease |g 6 -- |t The BEIR VII Risk Models |g 6 -- |t Research Reviewed by the Committee |g 9 -- |t Evidence from Biology |g 11 -- |t Estimation of Heritable Genetic Effects of Radiation in Human Populations |g 12 -- |t Evidence from Epidemiology |g 12 -- |t Integration of Biology and Epidemiology |g 14 -- |t Estimating Cancer Risks |g 14 -- |t Recommended Research Needs |g 15 -- |t Physical Aspects of Radiation |g 19 -- |t Chemical Aspects of Radiation |g 29 -- |t Molecular Mechanisms of DNA Repair |g 32 -- |g Annex 1A |t Ionizing Radiation and Oxidative Damage-A Viewpoint from Saccharomyces cerevisiae |g 40 -- |g 2 |t Molecular and Cellular Responses to Ionizing Radiation |g 43 -- |t General Aspects of Dose-Response Relationships |g 43 -- |t Induction of Chromosome Aberrations |g 45 -- |t Induction of Gene Mutations in Somatic Cells |g 46 -- |t Radiation-Induced Genomic Instability |g 47 -- |t Cell Cycle Effects |g 49 -- |t Adaptive Response |g 50 -- |t Bystander Effects |g 53 -- |t Hyper-Radiation Sensitivity at Low Doses |g 55 -- |t Observed Dose-Response Relationships at Low Doses |g 57 -- |g 3 |t Radiation-Induced Cancer: Mechanisms, Quantitative Experimental Studies, and the Role of Genetic Factors |g 65 -- |t Mechanisms of Tumorigenesis |g 66 -- |t Radiation-Induced Genomic Instability in Radiation Tumorigenesis |g 70 -- |t Quantitative Studies in Experimental Tumorigenesis |g 73 -- |t Genetic Susceptibility to Radiation-Induced Cancer |g 79 -- |g 4 |t Heritable Genetic Effects of Radiation in Human Populations |g 91 -- |t Introduction and Brief History |g 91 -- |t General Framework |g 92 -- |t Genetic Diseases |g 92 -- |t Risk Estimation Methods |g 93 -- |t Recent Advances with Respect to the Three Quantities Used with the DD Method of Risk Estimation |g 94 -- |t The Doubling Dose Estimate |g 101 -- |t Mutation Component of Genetic Diseases |g 101 -- |t MC Estimation for Chronic Multifactorial Disease |g 105 -- |t Other Potentially Relevant Data |g 113 -- |t Risk Estimation |g 114 -- |g Annex 4A |t Models of Inheritance of Multifactorial Diseases in the Population |g 120 -- |g Annex 4B |t The Doubling Dose |g 122 -- |g Annex 4C |t Assumptions and Specifications of the Finite-Locus Threshold Model |g 124 -- |g Annex 4D |t Differences Between Spontaneous Disease-Causing Mutations in Humans and Radiation-Induced Mutations in Experimental Systems |g 124 -- |g Annex 4E |t Criteria Used to Assign Human Genes to One of Three Groups from the Standpoint of the Recoverability of Induced Mutations in Live Births |g 125 -- |g Annex 4F |t Radiation Studies with Expanded Simple Tandem Repeat Loci in the Mouse and Minisatellite Loci in Human Germ Cells |g 125 -- |g Annex 4G |t Doubling Doses Estimated from Genetic Data of Children of A-Bomb Survivors |g 130 -- |g 5 |t Background for Epidemiologic Methods |g 132 -- |t Collection of Epidemiologic Data |g 133 -- |t Analysis of Epidemiologic Data |g 136 -- |t Interpretation of Epidemiologic Data |g 139 -- |g 6 |t Atomic Bomb Survivor Studies |g 141 -- |t Description of the Cohort |g 142 -- |t Statistical Methods |g 143 -- |t All Solid Cancers |g 144 -- |t Site-Specific Cancers |g 147 -- |t Cancers Resulting from Exposure In Utero |g 151 -- |t Benign Neoplasms |g 151 -- |t Nonneoplastic Disease |g 152 -- |t Life Shortening |g 153 -- |g 7 |t Medical Radiation Studies |g 155 -- |t Medical Uses of Radiation |g 156 -- |t Evaluation of Risk for Specific Cancer Sites |g 173 -- |g 8 |t Occupational Radiation Studies |g 189 -- |t Nuclear Industry Workers |g 190 -- |t Workers from the Mayak Facility |g 201 -- |t Chernobyl Cleanup Workers |g 202 -- |t Airline and Aerospace Employees |g 204 -- |t Medical and Dental Occupational Exposures |g 204 -- |g 9 |t Environmental Radiation Studies |g 207 -- |t Populations Living Around Nuclear Facilities |g 208 -- |t Populations Exposed from Atmospheric Testing, Fallout, or Other Environmental Release of Radiation |g 212 -- |t Populations Exposed from the Chernobyl Accident |g 215 -- |t Populations Exposed from Natural Background |g 228 -- |t Children of Adults Exposed to Radiation |g 228 -- |t Exposure to Radioactive Iodine 131 |g 233 -- |g 10 |t Integration of Biology and Epidemiology |g 239 -- |t DNA Damage Response and Cancer Risk |g 239 -- |t Projection of Risks Over Time |g 239 -- |t The Transport of Cancer Risk Between Different Populations |g 240 -- |t Form of the Dose-Response for Radiation Tumorigenesis |g 245 -- |t Dose and Dose-Rate Effects on Tumor Induction |g 246 -- |t Other Forms of Cellular and Animal Response to Radiation |g 250 -- |t Genetic Susceptibility to Cancer |g 251 -- |t Heritable Effects of Radiation |g 252 -- |g Annex 10A |t Application of the Moolgavkar and Knudson Two-Stage Clonal Expansion Model to the Transport of Radiation Cancer Risk |g 253 -- |g Annex 10B |t Evidence for the Connection Between Dose Effects and Dose-Rate Effects in Animal Experiments |g 254 -- |g 11 |t Risk Assessment Models and Methods |g 259 -- |t Risk Assessment Methodology |g 259 -- |t Risk Models |g 261 -- |t Variables That Modify the Dose-Response Relationship |g 264 -- |g 12 |t Estimating Cancer Risk |g 267 -- |t Data Evaluated for BEIR VII Models |g 267 -- |t Measures of Risk and Choice of Cancer End Points |g 268 -- |t The BEIR VII Committee's Preferred Models |g 269 -- |t Use of the Committee's Preferred Models to Estimate Risks for the U.S. Population |g 274 -- |t Quantitative Evaluation of Uncertainty in Lifetime Risks |g 278 -- |t Results of Risk Calculations |g 278 -- |t Uncertainties in Lifetime Risk Estimates |g 284 -- |t Coherence of Models with Other Studies |g 286 -- |g Annex 12A |t Previous Models for Estimating Cancer Risks from Exposure to Low Levels of Low-LET Ionizing Radiation |g 291 -- |g Annex 12B |t Committee Analyses of Data on the LSS Cohort to Develop BEIR VII Models for Estimating Cancer Risks |g 296 -- |g Annex 12C |t Details of LAR Uncertainty Analysis |g 308 -- |g Annex 12D |t Additional Examples of Lifetime Risk Estimates Based on BEIR VII Preferred Models |g 310 -- |g 13 |t Summary and Research Needs |g 313 -- |t Evidence from Biology |g 313 -- |t Genetic Effects of Radiation on Human Populations |g 316 -- |t Epidemiologic Studies of Populations Exposed to Ionizing Radiation |g 317 -- |t Integration of Biology and Epidemiology |g 321 -- |t Models for Estimating the Lifetime Risk of Cancer |g 322 -- |g A |t Basic Biological and Genetic Concepts |g 327 -- |g B |t Commentary on "Radiation From Medical Procedures in the Pathogenesis of Cancer and Ischemic Heart Disease: Dose-Response Studies with Physicians Per 100,000 Population" |g 329 -- |g C |t Issues Raised by the Institute for Energy and Environment Research (IEER) |g 330 -- |g D |t Hormesis |g 332 -- |g E |t Fifteen-Country Workers Study |g 336 |
| 505 | 8 | 0 | |t Epidemiologic Studies of Populations Exposed to Ionizing Radiation -- |t Integration of Biology and Epidemiology -- |t Models for Estimating the Lifetime Risk of Cancer -- |g A |t Basic Biological and Genetic Concepts -- |g B. |t Commentary on "Radiation From Medical Procedures in the Pathogenesis of Cancer and Ischemic Heart Disease: Dose-Response Studies with Physicians Per 100,000 Population" -- |g C. |t Issues Raised by the Institute for Energy and Environment Research (IEER) -- |g D. |t Hormesis -- |g E. |t Fifteen-Country Workers Study. |
| 505 | 8 | 0 | |t Populations Exposed from the Chernobyl Accident -- |t Populations Exposed from Natural Background -- |t Children of Adults Exposed to Radiation -- |t Exposure to Radioactive Iodine 131 -- |g 10 |t Integration of Biology and Epidemiology -- |t DNA Damage Response and Cancer Risk -- |t Projection of Risks Over Time -- |t The Transport of Cancer Risk Between Different Populations -- |t Form of the Dose-Response for Radiation Tumorigenesis -- |t Dose and Dose-Rate Effects on Tumor Induction -- |t Other Forms of Cellular and Animal Response to Radiation -- |t Genetic Susceptibility to Cancer -- |t Heritable Effects of Radiation -- |g Annex 10A. |t Application of the Moolgavkar and Knudson Two-Stage Clonal Expansion Model to the Transport of Radiation Cancer Risk -- |g Annex 10B. |t Evidence for the Connection Between Dose Effects and Dose-Rate Effects in Animal Experiments -- |g 11. |t Risk Assessment Models and Methods -- |t Risk Assessment Methodology -- |t Risk Models -- |t Variables That Modify the Dose-Response Relationship -- |g 12. |t Estimating Cancer Risk -- |t Data Evaluated for BEIR VII Models -- |t Measures of Risk and Choice of Cancer End Points -- |t The BEIR VII Committee's Preferred Models -- |t Use of the Committee's Preferred Models to Estimate Risks for the U.S. Population -- |t Quantitative Evaluation of Uncertainty in Lifetime Risks -- |t Results of Risk Calculations -- |t Uncertainties in Lifetime Risk Estimates -- |t Coherence of Models with Other Studies -- |g Annex 12A. |t Previous Models for Estimating Cancer Risks from Exposure to Low Levels of Low-LET Ionizing Radiation -- |g Annex 12B. |t Committee Analyses of Data on the LSS Cohort to Develop BEIR VII Models for Estimating Cancer Risks -- |g Annex 12C. |t Details of LAR Uncertainty Analysis -- |g Annex 12D. |t Additional Examples of Lifetime Risk Estimates Based on BEIR VII Preferred Models -- |g 13. |t Summary and Research Needs -- |t Evidence from Biology -- |t Genetic Effects of Radiation on Human Populations -- |
| 505 | 8 | 0 | |t Recent Advances with Respect to the Three Quantities Used with the DD Method of Risk Estimation -- |t The Doubling Dose Estimate -- |t Mutation Component of Genetic Diseases -- |t MC Estimation for Chronic Multifactorial Disease -- |t Other Potentially Relevant Data -- |t Risk Estimation -- |g Annex 4A |t Models of Inheritance of Multifactorial Diseases in the Population -- |g Annex 4B. |t The Doubling Dose -- |g Annex 4C. |t Assumptions and Specifications of the Finite-Locus Threshold Model -- |g Annex 4D. |t Differences Between Spontaneous Disease-Causing Mutations in Humans and Radiation-Induced Mutations in Experimental Systems -- |g Annex 4E. |t Criteria Used to Assign Human Genes to One of Three Groups from the Standpoint of the Recoverability of Induced Mutations in Live Births -- |g Annex 4F. |t Radiation Studies with Expanded Simple Tandem Repeat Loci in the Mouse and Minisatellite Loci in Human Germ Cells -- |g Annex 4G. |t Doubling Doses Estimated from Genetic Data of Children of A-Bomb Survivors -- |g 5. |t Background for Epidemiologic Methods -- |t Collection of Epidemiologic Data -- |t Analysis of Epidemiologic Data -- |t Interpretation of Epidemiologic Data -- |g 6. |t Atomic Bomb Survivor Studies -- |t Description of the Cohort -- |t Statistical Methods -- |t All Solid Cancers -- |t Site-Specific Cancers -- |t Cancers Resulting from Exposure In Utero -- |t Benign Neoplasms -- |t Nonneoplastic Disease -- |t Life Shortening -- |g 7. |t Medical Radiation Studies -- |t Medical Uses of Radiation -- |t Evaluation of Risk for Specific Cancer Sites -- |g 8. |t Occupational Radiation Studies -- |t Nuclear Industry Workers -- |t Workers from the Mayak Facility -- |t Chernobyl Cleanup Workers -- |t Airline and Aerospace Employees -- |t Medical and Dental Occupational Exposures -- |g 9. |t Environmental Radiation Studies -- |t Populations Living Around Nuclear Facilities -- |t Populations Exposed from Atmospheric Testing, Fallout, or Other Environmental Release of Radiation -- |
| 530 | |a Also available online via the World Wide Web | ||
| 530 | |a Also issued online | ||
| 590 | |a *jy 20061204 | ||
| 650 | 0 | |a Ionizing radiation |x Dose-response relationship | |
| 650 | 0 | |a Ionizing radiation |x Physiological effect | |
| 650 | 0 | |a Ionizing radiation |x Toxicology | |
| 650 | 7 | |a Ionizing radiation |x Dose-response relationship |2 fast | |
| 650 | 7 | |a Ionizing radiation |x Physiological effect |2 fast | |
| 650 | 7 | |a Ionizing radiation |x Toxicology |2 fast | |
| 650 | 1 | 2 | |a Radiation Injuries |
| 650 | 1 | 2 | |a Radiation, Ionizing |x toxicity |
| 650 | 1 | 2 | |a Radiation, Ionizing |
| 650 | 2 | 2 | |a Dose-Response Relationship, Drug |
| 650 | 2 | 2 | |a Dose-Response Relationship, Radiation |
| 650 | 2 | 2 | |a Radiation Effects |
| 650 | 2 | 2 | |a Risk Assessment |
| 710 | 2 | |a National Research Council (U.S.) |b Committee to Assess Health Risks from Exposure to Low Level of Ionizing Radiation. | |
| 830 | 0 | |a BEIR (Series) ; |v 7, phase 2 | |
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| 999 | 1 | 1 | |l 990014034770106761 |s ISIL:US-MCM |t BKS |a LSA OCC |b 39080028442538 |c RA1231.R2.H395 2006 |d 0 |x BOOK |y 23493045350006761 |p UNLOANABLE |
| 999 | 1 | 1 | |l 990037597320108501 |s ISIL:US-NCD |t BKS |a PERKN PK |b D03132216I |c RA1231.R2 H395 2006 |d 0 |x BOOK |y 23701402200008501 |p LOANABLE |
| 999 | 1 | 1 | |l 991006199769705706 |s ISIL:US-NHD |t BKS |a LCSF LCSF |b 33311019630930 |c RA1231.R2 H395 2006 |d 0 |x BOOK |y 23134324290005706 |p LOANABLE |
| 999 | 1 | 1 | |l 5606911 |s ISIL:US-NNC |t BKS |a off,sci |b CU11896248 |c RA1231.R2 H395 2006 |y 6018005 |p LOANABLE |
| 999 | 1 | 1 | |l 9939971903503681 |s ISIL:US-PU |t BKS |a BiomLib biom |b 31198043890404 |c RA1231.R2 H395 2006 |d 0 |x BOOK |y 23323958760003681 |p UNLOANABLE |