3D printing in medicine /

3D Printing in Medicine, Second Edition examines the rapidly growing market of 3D-printed biomaterials and their clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The chapt...

Full description

Bibliographic Details
Corporate Authors: President Emeritus Martin Meyerson Fund, ProQuest ebook central
Other Authors: Kalaskar, Deepak M. (Editor)
Format: Book
Language:English
Published: Cambridge, MA ; Kidlington, United Kingdom Woodhead Publishing, [2023]
Cambridge, MA ; Kidlington, United Kingdom [2023]
Edition:Second edition
Series:Woodhead Publishing series in biomaterials
Subjects:
Table of Contents:
  • Front Cover
  • 3D Printing in Medicine
  • Copyright Page
  • Contents
  • List of contributors
  • Preface
  • 1 Introduction to three-dimensional printing in medicine
  • 1.1 3D printing is the latest industrial revolution
  • 1.1.1 Brief history of 3D printing
  • 1.1.2 Basic components of 3D printing
  • 1.2 3D bioprinting in medicine
  • 1.2.1 3D bioprinting approaches
  • 1.2.1.1 Biomimicry
  • 1.2.1.2 Independent self-assembly
  • 1.2.1.3 Miniature-tissue blocks
  • 1.2.2 Feasibility of organ printing technology
  • 1.2.3 In vivo behavior of 3D printed organ constructs
  • 1.3 Advantages of 3D printing for medicine
  • 1.3.1 Applications of 3D printing in medicine
  • 1.3.1.1 3D printing for surgical templates and diagnostic tools
  • 1.3.1.2 Organ printing technology
  • 1.3.1.3 3D disease modeling
  • 1.3.1.4 3D printing for commercial pharmaceutical products
  • 1.3.1.5 4D bioprinting
  • 1.3.2 Limitations and challenges of 3D printing
  • 1.4 Future of 3D printing in medicine
  • 1.5 Regulation, intellectual property, ethics and standards for 3D printing in medicine
  • 1.5.1 Commercial 3D bioprinters
  • 1.5.2 International standards and regulatory framework of 3D bioprinting
  • 1.5.2.1 International standards used for 3D bioprinting
  • 1.5.2.2 Regulatory authorities and guidelines
  • 1.5.3 Intellectual property and socio-ethical implications of organ 3D printing
  • 1.5.3.1 Intellectual property in 3D bioprinting
  • 1.5.3.2 Ethics and social concerns of organs on demand
  • References
  • 2 3D printing families: laser, powder, and nozzle-based techniques
  • 2.1 Introduction
  • 2.2 Classification of 3D printing techniques
  • 2.2.1 Resin-based systems
  • 2.2.2 Powder-based systems
  • 2.2.3 Extrusion-based systems
  • 2.2.4 Droplet-based systems
  • 2.3 Challenges and Food and Drug Administration regulations
  • 2.4 Conclusions and future trends
  • Acknowledgments
  • 4.4.3 Enriching the knowledge of cardiovascular biomechanics with combination of computational and 3D printed models
  • 4.4.4 Planning procedures
  • 4.5 Patient-specific models: the current perspective of regulatory bodies and policy makers
  • 4.6 Future perspective of patient-specific models in cardiovascular applications
  • References
  • 5 3D printers for surgical practice
  • 5.1 Introduction
  • 5.2 Imaging to printed model: steps involved
  • 5.3 Limitations of CT and MRI images for surgical planning
  • 5.4 3D printed models for anatomical simulation for surgeons
  • 5.4.1 Orthopedic tissues
  • 5.4.2 Cardiac surgery: heart valve surgery
  • 5.4.3 Neurosurgery
  • 5.4.4 Malignant tissues
  • 5.5 Surgical planning of congenital anomalies
  • 5.6 3D printed models for anatomical teaching
  • 5.7 Tissue defect-specific implant design
  • 5.8 3D printing for surgical templates and diagnostic tools
  • 5.9 Advantages of 3D printed models
  • 5.10 Challenges for 3D printed models
  • 5.11 Legal and ethical issues for 3D printing in surgery
  • 5.12 Conclusion
  • References
  • 6 Patient-specific 3D bioprinting for in situ tissue engineering and regenerative medicine
  • 6.1 Patient-specific 3D printing
  • 6.1.1 Personalized medicine
  • 6.1.2 Introduction to 3D printing technology: 3D printing in personalized medicine
  • 6.1.3 Patient-specific 3D model creation and application of machine learning and artificial intelligence algorithms
  • 6.2 Current medical applications for 3D printing
  • 6.2.1 3D bioprinting of vascularized organs and tissues in vitro
  • 6.2.2 3D bioprinting of organs for personalized drug screening and disease modeling
  • 6.2.3 In situ 3D bioprinting directly to the defect/wound site
  • 6.2.3.1 Wound repair
  • 6.2.3.2 Bone defect repair
  • 6.3 Challenges and future advancements
  • 6.4 Summary
  • References
  • 7 3D-bioprinted in vitro disease models
  • 7.1 Introduction
  • 7.2 Bioinks
  • 7.3 3D disease modeling
  • 7.3.1 Cancer modeling
  • 7.3.2 Tissues models and new therapies screening
  • 7.3.2.1 3D printed osteoarthritis models
  • 7.4 Concluding remarks and future prospects
  • Acknowledgments
  • References
  • 8 3D printed pharmaceutical products
  • 8.1 Introduction
  • 8.2 Pharmaceutical 3D printing
  • 8.2.1 Material extrusion
  • 8.2.1.1 Fused filament fabrication
  • Benefits
  • Challenges and solutions
  • 8.2.1.2 Pneumatic extrusion
  • Benefits
  • Challenges and solutions
  • 8.2.2 Vat-based 3D printing
  • 8.2.2.1 Benefits
  • 8.2.2.2 Challenges and solutions
  • 8.2.3 Powder bed fusion: selective laser sintering
  • 8.2.3.1 Benefits, challenges and solutions
  • 8.2.4 Inkjet-based 3D printing
  • 8.2.4.1 Benefits, challenges and solutions
  • 8.3 Active pharmaceutical ingredients synthesis and assessment using 3D printing
  • 8.4 Conclusions
  • References
  • 9 High-resolution 3D printing for healthcare
  • 9.1 Clinical need and context
  • 9.2 High-resolution 3D printing
  • 9.3 Types of high-resolution 3D printing
  • 9.3.1 Direct-write printing
  • 9.3.2 Electrohydrodynamic printing
  • 9.3.3 3D direct laser writing
  • 9.3.4 Focused ion beam
  • 9.3.5 Digital light process and two-photon photolithography
  • 9.4 Fundamentals of micro/nanofluidics
  • 9.4.1 Micro/nanofluidics
  • 9.4.2 Ink properties: preliminary aspects of rheology
  • 9.4.3 Viscoelasticity
  • 9.4.4 Wetting
  • 9.4.5 Evaporation
  • 9.4.6 Dynamic effects
  • 9.5 Printing materials
  • 9.5.1 Nonbiologic printing materials
  • 9.5.2 Bioink printing
  • 9.6 Exemplar functional devices
  • 9.6.1 Interconnects
  • 9.6.2 Site-specific deposition
  • 9.6.3 Healthcare sensors
  • 9.6.4 Implantable devices
  • 9.6.5 Printed bioscaffolds
  • 9.6.6 Mechanobiology and cell signaling studies
  • 9.6.7 Biomedical microrobots
  • 9.7 Conclusions and future direcions